Immunology research update from Immunopaedia.org.za. A Recent study demonstrates the role of the C5a-C5aR1 axis in the promoting immunopathology associated with cobra venom. These findings have potential implications for the development of novel snake bite immunotherapy.
COVID-19 and SARS-CoV-2 update from Immunopaedia.org.za. Studies suggest that a single dose of BNT162b2 confers the same benefit as two doses given to those with or without previous SARS-CoV-2 infection; this may be crucial for vaccine distribution programs as a single shot could be sufficient in previously infected people.
Immunology research update from Immunopaedia.org.za. Since nothing is known about aged neutrophils in cancer biology and mature neutrophils in the circulation are considered to be heterogenous, Peng et al. examined how metastatic cancers regulate mature neutrophils. To this end, they induced tumor growth in mice by injecting cells from breast cancer..
Immunology research update from Immunopaedia.org.za. P.falciparum is able to modulate the RBC’s membrane stiffness. However, can P.falciparum remodel naïve surrounding RBCs in preparation for invasion while growing inside their host RBC?
Immunology research update from Immunopaedia.org.za. Damelang et al. investigated the ability of IgG antibodies, specific to DBL2 and DBL3 (two VAR2CSA domains), of pregnant women from a malaria-endemic area to activate human primary NK cells from malaria-naïve donors.
Join the next IUIS (International Union of Immunological Societies), Immunopaedia and Frontiers webinar on Regulatory B cells and gut-microbiota: an intricate acting balance in autoimmunity with Claudia Mauri. LIVE on May 10, 15:00 CET
Immunology research update from Immunopaedia.org.za. HPV infection is attributable to about 99.7% of cervical cancer cases globally in addition to other anogenital and oropharyngeal cancers. Researchers have recently published data from Rwanda and Bhutan that demonstrate HPV vaccine effectiveness in LMICs.
COVID-19 and SARS-CoV-2 update from Immunopaedia.org.za. Article in the American Society of Microbiology outlined how differences in expression within lung tissue may impact the effect of SARS-CoV-2 infection on the individual.
Immunology research update from Immunopaedia.org.za. Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease that occurs at any age and mainly affects women. Understanding the immunopathogenesis of AIH is crucial for the development of treatment strategies
Join the next IUIS (International Union of Immunological Societies), Immunopaedia and Frontiers webinar on Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 with Qian Zhang. LIVE on April 19, 15:00 CET
COVID-19 and SARS-CoV-2 update from Immunopaedia.org.za. Moyo-Gwete et al., 2021 demonstrated that 501Y.V2 elicits robust neutralizing antibody responses against both the original variant and 501Y.V3 (P.1), which indicates high levels of cross-reactivity. Watch video summary for..
Immunology research update from Immunopaedia.org.za. Using a systematic search for antibodies that bind broadly to infected erythrocytes, they discovered a new class of Abs generated by insertions of genomic DNA encoding human inhibitory receptors (LAIR1) into antibody genes.