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Progression from Infection to Pulmonary Tuberculosis Follows Distinct Timeline
Researchers from SATVI in our Division have uncovered a sequence of biological processes that occur as M. tuberculosis infection progresses to symptomatic disease, according to new research published in the PLOS Pathogens Journal.
DNA minor groove binders as potential antitubercular drugs
In a report recently published in the Journal of Antimicrobial Therapy, Division of Immunology researchers including Lerato Hlaka, Michael-Jon Rosslee, and Reto Guler describe new potential antitubercular drugs that bind to the minor groove of DNA.
Congratulations to Dr. Mohlopheni Marakalala
Congratulations to our own Dr. Mohlopheni Marakalala, who has been awarded a Wellcome Trust Intermediate Fellowship in Public Health and Tropical Medicine!
Colon Goblet cells Hoving
IL-13 is able to drive colitis in the absence of IL-4Rα
Recent work by Claire Hoving and Frank Brombacher published in GUT, highlights that IL-13 is able to drive colitis in the absence of IL-4Rα. This raises hope for anti-IL-13 treatment for ulcerative colitis patients.
Compartmentalization of pro- and anti-inflammatory responses
Tracking pro- and anti-inflammatory responses to tuberculosis
A study led by the recently-appointed Senior Lecturer, Dr Mohlopheni J Marakalala, shows that pro- and anti-inflammatory responses are spatially compartmentalized to distinct regions within human tuberculosis granulomas.

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News

Thursday, 18 January 2018
Immunopaedia
Immunopaedia News

Interesting Immunology news at Immunopaedia Breaking News

Publication Date:
Tuesday, May 2, 2017 - 00:45
Insight into immune defects of HIV-exposed uninfected infants

New work gives insight into a possible mechanism for immune and other health defects in HIV-1 exposed, uninfected infants. UCT Immunology researcher Dr. Heather Jaspan contributed to this work. Levels of Ochratoxin A, a natural and common food contaminant, are associated with T cell activation in HIV-1 exposed, uninfected infants.

Read the publication here

Publication Date:
Thursday, December 28, 2017 - 14:15
DNA minor groove binders as potential antitubercular drugs

In a report recently published in the Journal of Antimicrobial Therapy, Division of Immunology researchers including Lerato Hlaka, Michael-Jon Rosslee, and Reto Guler describe new potential antitubercular drugs that bind to the minor groove of DNA.  

Read the publication here.

Publication Date:
Thursday, November 30, 2017 - 23:15