Worms can affect vaccine efficacy: lessons for COVID-19?
Fungai Musaigwa (PhD candidate in the Division of Immunology) and his supervisor ,Dr Justin Nono Komguep, published an article in The Conversation on 12 September 2021 entitled "Worms can affect vaccine efficacy: lessons for COVID-19?". Fungai was then interviewed by Africa Melane on the Early Breakfast show, Cape Talk FM, a few days later. The article and interview focus on how parasitic worms can affect vaccine efficacy.
Deletion of IL-4Rα signaling on B cells limits hyperresponsiveness depending on antigen load
Division of Immunology and ICGEB researchers Dr Sabelo Hadebe, Dr Jermaine Khumalo, Dr Martyna Scibiorek, Ms Amkele Ngomti, Ms Nontobeko Mthembu, Ms Sandisiwe Mangali, Dr Hlumani Ndlovu, Dr Frank Kirstein and Professor Frank Brombacher, recently authored a paper in JACI. The paper published in December 2020 is entitled "Deletion of IL-4Rα signaling on B cells limits hyperresponsiveness depending on antigen load". The paper was highlighted in The Editors’ Choice, JACI.
Hormonal contraception alters vaginal microbiota and cytokines in SA adolescents
Division of Immunology researchers; Dr Christine Balle (first author), Dr Shameem Z. Jaumdally, Dr Anna-Ursula Happel, Rachel Esra, Enock Havyarimana and Dr Heather Jaspan recently authored a paper in Nature Communications. The paper published in November 2020 is entitled “Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial”.
IL-4Rα signaling in CD4+CD25+FoxP3+ T regulatory cells restrains airway inflammation via limiting local tissue IL-33
Division of Immunology and ICGEB researchers Dr Jermaine Khumalo, Dr Frank Kirstein, Dr Sabelo Hadebe and Professor Frank Brombacher, recently authored a paper in JCI Insight. The paper published in September 2020 is entitled “IL-4Rα signaling in CD4+CD25+FoxP3+ T regulatory cells restrains airway inflammation via limiting local tissue IL-33”
Division of Immunology and ICGEB researchers Dr Tiroyaone M Brombacher, (PhD) Inssaf Berkiks, (PhD) Shandre Pillay, (MSc) Martyna Scibiorek, (MSc) Blessing O. Moses (BSc) and Professor Frank Brombacher (PhD), recently authored a paper in Scientific Reports. The paper published in October 2020 is entitled “IL-4R alpha deficiency influences hippocampal-BDNF signaling pathway to impair reference memory”.
Immunology research update from www.immunopaedia.org.za. Researchers have now developed a novel therapy concept for programming the tumour cells to produce a CD47-blocking and immune-activation fusion protein in the hope that this will halt tumour growth…
Immunology research update from www.immunopaedia.org.za. In a recent study conducted by researchers at the Rega Institute for Medical Research, KU Leuven, have identified and developed an ultrapotent inhibitor of the dengue virus (DENV), which causes the tropical disease known as dengue.
Immunology research update from www.immunopaedia.org.za. Researchers have investigated and described the rate of changes in peripheral blood white cells (WBCs) in individuals who have recovered from SARS-CoV-2 infection, comparing the differences to alterations seen with other mild respiratory infections.
Immunology research update from www.immunopaedia.org.za. Researchers from the Wellcome Sanger Institute, Newcastle University and their collaborators have performed a comprehensive analysis of how the blood and immune systems develop in prenatal bone marrow…
‘Driving science to promote world health’ with an emphasis on cutting-edge research, training students and staff, mentoring and enhancing research capacity in South Africa.
To use an integrated cohesive immunology programme of research, education and service to combat communicable and non-communicable diseases in South Africa and beyond.
UCT has a strong track record in immunology and aims to become the centre of research in Africa. Most of the research projects are internationally collaborative which is essential for meaningful research.